Scientific Research

The lead researcher, M. Elizabeth Sublette MD PhD, has authored several articles on the topic of fatty acids and mood disorders:

…concerning effectiveness of omega-3 supplements in clinical trials

Read the abstract here:

Meta-Analysis of the Effects of Eicosapentaenoic Acid (EPA) in Clinical Trials in Depression. J. Clin Psychiatry

New York State Psychiatric Institute

New York State Psychiatric Institute

…concerning relationships between manic symptoms and fatty acid blood levels in people with bipolar disorder

Read the abstract here:

Plasma free polyunsaturated fatty acid levels are associated with symptom severity in acute mania. Bipolar Disord (2007) vol. 9 (7) pp. 759-65.

…about brain functioning and fatty acid blood levels in depressed people

Read the abstract here:

Plasma polyunsaturated fatty acids and regional cerebral glucose metabolism in major depression. Prostaglandins Leukot Essent Fatty Acids (2009)

…about fatty acid blood levels and subsequent suicide attempts in people with depression

Read the abstract here:

Omega-3 Polyunsaturated Essential Fatty Acid Status as a Predictor of Future Suicide Risk (2006) .

…about fatty acids and anxiety

Read the abstract here:

Omega-3 Polyunsaturated Essential Fatty Acid (PUFA) Status in Major Depressive Disorder with Comorbid Anxiety Disorders (2013).

…and a review of the scientific literature connecting fatty acids and mood (affective) disorders

Read the abstract here:

Evidence for a role of the arachidonic acid cascade in affective disorders: a review (2004) .

Are you interested in helping advance the understanding of  fatty acids and brain function?

We are currently seeking participants for our research study. If eligible, you would receive $350 compensation, FREE medical and psychiatric evaluations (including lab work) and up to six months of medication treatment with Columbia Presbyterian doctors. Please call Corinne at (646) 774-7560 today to see if you are eligible to participate.

We are now recruiting people to participate in a research study that investigates the effects of fatty acids in bipolar depression.



You may be able to help our efforts by participating in an NIH-funded research study. [Learn More]
Funded by: R-21 exploratory/developmental research grant MH096255