Scientific Research

The lead researcher, M. Elizabeth Sublette MD PhD, has authored several articles on the topic of fatty acids and mood disorders:

…concerning effectiveness of omega-3 supplements in clinical trials

Read the abstract here:

Meta-Analysis of the Effects of Eicosapentaenoic Acid (EPA) in Clinical Trials in Depression. J. Clin Psychiatry

…concerning relationships between manic symptoms and fatty acid blood levels in people with bipolar disorder

Read the abstract here:

Plasma free polyunsaturated fatty acid levels are associated with symptom severity in acute mania. Bipolar Disord (2007) vol. 9 (7) pp. 759-65.

…about brain functioning and fatty acid blood levels in depressed people

Read the abstract here:

Plasma polyunsaturated fatty acids and regional cerebral glucose metabolism in major depression. Prostaglandins Leukot Essent Fatty Acids (2009)

…about correlations between fatty acid blood levels and subsequent suicide attempts in people with depression

Read the abstract here:

Omega-3 Polyunsaturated Essential Fatty Acid Status as a Predictor of Future Suicide Risk (2006) .

…and a review of the scientific literature connecting fatty acids and mood (affective) disorders

Read the abstract here:

Evidence for a role of the arachidonic acid cascade in affective disorders: a review (2004) .

Are you interested in helping advance the understanding of omega-3 fatty acids and brain function?

We are currently seeking participants for our research study. If eligible, you would receive $300 compensation, FREE medical and psychiatric evaluations (including lab work) and up to six months of medication treatment with Columbia Presbyterian doctors. Please call Katherin at (212) 543-5834 today to see if you are eligible to participate.

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Please note: No compensation is offered for either the telephone screening or the in-person visit. You must be enrolled in the research study to receive the compensation of $300, psychiatric and medical evaluations, diagnostic blood work, and professional treatment.

If you are eligible for the research study, we will explain all procedures, risks, and benefits of the research study and your rights as a research participant.

If you are not eligible for this research study, you may still be eligible for another study at Columbia University. We will refer you to other study resources.

Fish Oil and Depression

A number of scientific studies reveal that omega-3 fatty acids, such as those found in certain cold-water fish, play an important role in the proper functioning of the human brain, and that people with depression tend to have lower levels of omega-3 in their bodies...[Learn More]

About Omega-3 Fatty Acids

Omega-3 fatty acids are one type of “essential” dietary fatty acids. This means that the human body needs them for health but cannot make them. We must get these compounds through the foods we eat...[Learn More]